Studies on Royal Jelly and Abnormal Cholesterol and Triglycerides
Young T. Cho, MD - Director, Department of Laboratories at St. Mary's Hospital, New York
Reprinted with permission from the American Bee Journal

Heart attack is a number one killer in the nation. High cholesterol and Triglycerides, collectively called lipids, are associated with heart attack, strokes, atherosclerosis and arteriosclerosis (hardening of the blood vessels). To lower serum triglycerides and cholesterol we may be on a prolonged low calorie diet or on anticholesterol medicine such as clofivrate (Atromid S or L-Lysine). The lowering effect of royal jelly on abnormal cholesterol in experimental rabbits was reported first by Luis Guillermo Cornejo et al in 1973. This experiment showed significant control of cholesterol in rabbit blood, while a high cholesterol diet was given together with royal jelly.
What is Royal Jelly?
Royal Jelly is a thick, milky food which is a secretion of the pharyngeal glands of the young nursing worker bees.

The greater nutritional significance of the royal jelly is the fact that the anatomical and functional differentiation of the female bee larvae is dependent upon the nature of their diet in their early developmental stage. The fertilized eggs give rise to females, either sexually immature small workers or large and fertile queens. All female larvae are fed on royal jelly for the first three days after hatching. Only the queen continues to be fed by royal jelly.

The queen bee is mother to a quarter of a million bees and lays more that 2,000 eggs in one day. The life span of the queen may be four to five years compared to the considerably short life of workers - usually 6 months or less. The unusual nature of royal jelly has prompted many investigations into its chemical nature and pharmacological properties, but the mystery of this material has yet to be completely understood.
Composition of Royal Jelly
Royal jelly has the following composition: Moisture 66.05%, protein 12.34%, total lipids 5.46%, total reducing substances 12.49%, Ash .62%. Undetermined 2.84%. Royal jelly is a good source of Vitamin B1, 1.0 to 1.5 International Units per Gram. No demonstrable amount of Vitamin A, Vitamin C or Vitamin E is present.

Royal jelly has been separated into four major fractions. Fraction 1 is either soluble material which consists of an organic acid (phenolic material and beeswax, sterol, phospholipin and a saponifiable substance). Fraction 2, water soluble and dialysable, the largest fraction, is about 50% sugar and unidentified acid inorganic salts and nitrogen compounds. Fraction 3, water soluble, non-dialysable, is protein in nature. This includes aspartic acid, arginine and tyrosine, trytophan and histidine. Fraction 4, water insoluble in a protein, soluble only in alkali. It is believed to be tyrosine, trytophan and arginine.

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